Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747229 | 1.00 | MEN1 (0.41) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL13616362 | 0.92 | MEN1 (0.39) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3425534 | 0.84 | MEN1 (0.44) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3425537 | 0.84 | MEN1 (0.44) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3429057 | 0.82 | GRIN1 (0.45) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3400342 | 0.82 | GRIN1 (0.45) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3400337 | 0.82 | GRIN1 (0.45) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL3429056 | 0.82 | GRIN1 (0.45) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL13616364 | 0.79 | MEN1 (0.43) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616363 | 0.79 | MEN1 (0.43) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097695-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | CHLORION PHARMA, INC. (CA) | 2009-08-13 | — | — | WO | disclosed |