Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 10/20 | 0.43 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.41 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748052 | 0.91 | MAP2K1 (0.54) | MAP2K1MAP2K2MAP2K5EIF2AK1PIM1 | |
| Trifluoromethanesulfonic Acid SCHEMBL929183 | 0.91 | MAP2K1 (0.38) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL929529 | 0.84 | MAP2K1 (0.47) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL929220 | 0.77 | MAP2K1 (0.43) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL390239 | 0.73 | MAP2K1 (0.68) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL188153 | 0.71 | MAP2K1 (0.49) | MAP2K1MAP2K2 | |
| SCHEMBL5992602 | 0.71 | MAP2K1 (0.74) | MAP2K1MAP2K2MAP2K5PIM1CAMK2B | |
| SCHEMBL29781367 | 0.71 | MAP2K1 (0.74) | MAP2K1MAP2K2MAP2K5PIM1CAMK2B | |
| SCHEMBL29413386 | 0.71 | MAP2K1 (0.49) | MAP2K1MAP2K2 | |
| SCHEMBL23694186 | 0.70 | MAP2K1 (0.52) | MAP2K1MAP2K2MAP2K5PIM1CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009101432-A2 | PROCESS FOR PREPARING PYRIDONE DERIVATIVES 226 | ASTRAZENECA AB (SE) | 2009-08-20 | — | — | WO | disclosed |