Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746929 | 0.95 | MEN1 (0.37) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13747082 | 0.94 | MEN1 (0.37) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616077 | 0.93 | MEN1 (0.39) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616078 | 0.92 | MEN1 (0.37) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13747080 | 0.91 | MEN1 (0.40) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616072 | 0.88 | MEN1 (0.38) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616076 | 0.87 | MEN1 (0.38) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13747010 | 0.87 | NPC1 (0.38) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616105 | 0.87 | NPC1 (0.38) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL13616098 | 0.86 | MEN1 (0.38) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097695-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | CHLORION PHARMA, INC. (CA) | 2009-08-13 | — | — | WO | disclosed |