Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668084 | 1.00 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL19783843 | 1.00 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL13618972 | 1.00 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL15016061 | 0.90 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL15016060 | 0.90 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL13696126 | 0.90 | BTK (0.51) | BTKKMT2AKDM1AMAOBMAOA | |
| SCHEMBL13696102 | 0.87 | BTK (0.37) | BTKKDM1AMAOBMAOASYK | |
| SCHEMBL13618997 | 0.87 | BTK (0.37) | BTKKDM1AMAOBMAOASYK | |
| SCHEMBL13618973 | 0.87 | BTK (0.37) | BTKKDM1AMAOBMAOASYK | |
| SCHEMBL13631330 | 0.87 | BTK (0.37) | BTKKDM1AMAOBMAOASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576135-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576135-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |