Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.34 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.34 |
| ▸ | PLD2 | O14939 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062476 | 0.72 | CALCRL (0.39) | CALCRLKCNH2 | |
| SCHEMBL3773551 | 0.64 | CALCRL (0.47) | CALCRLRAMP1MRGPRX2KCNH2 | |
| SCHEMBL15935917 | 0.59 | KCNH2 (0.37) | PLD2PLD1KCNH2 | |
| SCHEMBL437761 | 0.58 | CALCRL (0.56) | CALCRLKCNH2 | |
| SCHEMBL15701572 | 0.58 | CALCRL (0.56) | CALCRLKCNH2 | |
| SCHEMBL15935909 | 0.58 | CALCRL (0.39) | CALCRLRAMP1MRGPRX2KCNH2 | |
| SCHEMBL30032839 | 0.58 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL18812885 | 0.58 | CALCRL (0.62) | CALCRLRAMP1MRGPRX2KCNH2 | |
| SCHEMBL31318615 | 0.57 | CALCRL (0.66) | CALCRLRAMP1MRGPRX2KCNH2 | |
| SCHEMBL30032838 | 0.56 | KCNH2 (0.31) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105348-A1 | IMIDAZOBENZAZEPINE CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-08-27 | — | — | WO | disclosed |