Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.65 |
| ▸ | YES1 | P07947 | 1/20 | 0.43 |
| ▸ | FGR | P09769 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207651 | 0.88 | BTK (0.69) | BTKYES1FGRTECBMX | |
| SCHEMBL1726893 | 0.86 | BTK (0.67) | BTKYES1FGRTECBMX | |
| SCHEMBL3199695 | 0.85 | BTK (0.66) | BTKYES1FGRTECBMX | |
| SCHEMBL1727468 | 0.84 | BTK (0.65) | BTKYES1FGRTECBMX | |
| SCHEMBL13139771 | 0.83 | BTK (0.57) | BTKYES1FGRTECBMX | |
| SCHEMBL3214557 | 0.83 | BTK (0.63) | BTKYES1FGRTECBMX | |
| SCHEMBL3210750 | 0.82 | BTK (0.65) | BTKYES1FGRTECBMX | |
| SCHEMBL3220129 | 0.82 | BTK (0.66) | BTKYES1FGRTECBMX | |
| SCHEMBL3207537 | 0.81 | BTK (0.73) | BTKYES1FGRTECBMX | |
| SCHEMBL3207086 | 0.81 | BTK (0.81) | BTKYES1FGRTECBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098144-A1 | NOVEL PYRIDINONES AND PYRIDAZINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-13 | — | — | WO | disclosed |