SCHEMBL13748632

SCHEMBL13748632

C[C@@H](NCC1CCN(C(=O)CCCC(=O)N=O)CC1c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CASR P41180 17/20 0.42
CCR5 P51681 1/20 0.40
CYP2D6 P10635 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105872 0.92 CASR (0.44) CASRCCR5CYP2D6
SCHEMBL13749170 0.91 CASR (0.41) CASRCCR5CYP2D6
SCHEMBL1106022 0.91 CASR (0.44) CASRCCR5CYP2D6
SCHEMBL13748654 0.90 CASR (0.37) CASRCCR5
SCHEMBL1105890 0.90 CASR (0.43) CASRCCR5CYP2D6
SCHEMBL1105862 0.90 CASR (0.43) CASRCCR5CYP2D6
SCHEMBL1105940 0.90 CASR (0.43) CASRCCR5CYP2D6
SCHEMBL1105949 0.90 CASR (0.43) CASRCCR5CYP2D6
SCHEMBL13749117 0.89 CASR (0.42) CASRCYP2D6
SCHEMBL1106019 0.89 CASR (0.46) CASRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085383-A1 PIPERIDINE DERIVATIVES OR SALTS THEREOF Astellas Pharma Inc. (JP) 2009-08-05 EP disclosed