Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860088 | 0.79 | EPHX1 (0.43) | EPHX1ALDH1A1KAT2BBAZ2BCTSL | |
| SCHEMBL8371398 | 0.77 | EPHX1 (0.68) | EPHX1ALDH1A1KMT2AMEN1KAT2B | |
| SCHEMBL16114964 | 0.76 | USP2 (0.38) | EPHX1USP2SMN1; SMN2RECQLCTSD | |
| SCHEMBL2159267 | 0.76 | KMT2A (0.49) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL23366889 | 0.74 | KMT2A (0.45) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7821456 | 0.74 | KAT2B (0.39) | EPHX1SMN1; SMN2KAT2BBAZ2B | |
| SCHEMBL12335551 | 0.73 | EPHX1 (0.50) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL24325888 | 0.73 | KAT2B (0.37) | EPHX1USP2SMN1; SMN2RECQLKAT2B | |
| SCHEMBL1927025 | 0.73 | AAK1 (0.35) | EPHX1USP2SMN1; SMN2RECQLKAT2B | |
| SCHEMBL125503 | 0.72 | TDP1 (0.52) | EPHX1ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | disclosed |