Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748641 | 0.93 | MCHR1 (0.43) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL13748352 | 0.92 | MCHR1 (0.43) | MCHR1 | |
| SCHEMBL13748357 | 0.89 | MCHR1 (0.41) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL4050690 | 0.89 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL4047406 | 0.89 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL13748119 | 0.89 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL13748049 | 0.87 | MCHR1 (0.40) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL13747935 | 0.86 | MCHR1 (0.39) | MCHR1 | |
| SCHEMBL13748381 | 0.85 | MCHR1 (0.47) | MCHR1KCNH2 | |
| SCHEMBL13748500 | 0.84 | MCHR1 (0.38) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |