Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 9/20 | 0.48 |
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375392 | 0.90 | MAPT (0.51) | MAPTTP53CNR1CNR2POLB | |
| Hydrochloric Acid SCHEMBL1374910 | 0.89 | MAPT (0.50) | MAPTTP53CNR1CNR2POLB | |
| SCHEMBL1374656 | 0.87 | MAPT (0.48) | MAPTTP53CNR1CNR2POLB | |
| SCHEMBL1373635 | 0.82 | CNR1 (0.65) | CNR1CNR2TDP1LMNA | |
| SCHEMBL1375910 | 0.81 | MAPT (0.44) | MAPTTP53CNR1CNR2POLB | |
| SCHEMBL1372638 | 0.81 | MAPT (0.46) | MAPTTP53CNR1CNR2POLB | |
| SCHEMBL1376584 | 0.75 | CNR2 (0.46) | CNR1CNR2 | |
| SCHEMBL1372681 | 0.73 | CNR1 (0.66) | CNR1CNR2LMNA | |
| SCHEMBL1373592 | 0.72 | AHR (0.60) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL1373638 | 0.72 | CNR1 (0.65) | CNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | MAPT 4708/4885TP53 3811/4885CNR1 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.