SCHEMBL13749445

SCHEMBL13749445

C[C@@H](NCC1CN(C(=O)C2CCCCC2C(=O)N=O)CCC1c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CASR P41180 17/20 0.41
CYP2D6 P10635 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105918 0.92 CASR (0.43) CASRCYP2D6
SCHEMBL1105845 0.90 CYP2D6 (0.44) CASRCYP2D6
SCHEMBL13749313 0.86 CASR (0.41) CASRCYP2D6
SCHEMBL1105879 0.85 CASR (0.43) CASRCYP2D6
SCHEMBL1106011 0.84 CASR (0.42) CASRCYP2D6
SCHEMBL1105874 0.83 CYP2D6 (0.44) CASRCYP2D6
SCHEMBL1105919 0.83 CYP2D6 (0.47) CASRCYP2D6
SCHEMBL1105835 0.83 CYP2D6 (0.47) CASRCYP2D6
SCHEMBL13749117 0.83 CASR (0.42) CASRCYP2D6
SCHEMBL1106003 0.82 CASR (0.47) CASRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085383-A1 PIPERIDINE DERIVATIVES OR SALTS THEREOF Astellas Pharma Inc. (JP) 2009-08-05 EP disclosed