Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16931393 | 0.79 | ERN1 (0.47) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL2272244 | 0.75 | MAPT (0.66) | MAPTKDM4EMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9534267 | 0.73 | MAPT (0.63) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL23884574 | 0.72 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL2919847 | 0.72 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL1072434 | 0.72 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL7573563 | 0.72 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL12846492 | 0.70 | CYP2A6 (0.39) | — | |
| SCHEMBL4083790 | 0.70 | CHEK1 (0.46) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL25242753 | 0.69 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |