Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661897 | 1.00 | PPM1D (0.31) | PPM1D | |
| SCHEMBL13661904 | 0.90 | PPM1D (0.31) | PPM1D | |
| SCHEMBL13751228 | 0.90 | PPM1D (0.31) | PPM1D | |
| SCHEMBL13661929 | 0.86 | — | — | |
| SCHEMBL13751282 | 0.86 | — | — | |
| SCHEMBL13661913 | 0.82 | — | — | |
| SCHEMBL13661944 | 0.81 | — | — | |
| SCHEMBL13751226 | 0.81 | — | — | |
| SCHEMBL13661895 | 0.81 | — | — | |
| SCHEMBL19964283 | 0.79 | PPM1D (0.33) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576089-B2 | 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION | 2009-08-18 | — | — | US | disclosed |