Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 10/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13752964 | 0.91 | ZAP70 (0.46) | ZAP70CD274PDGFRBPDGFRA | |
| SCHEMBL13753060 | 0.87 | ZAP70 (0.42) | ZAP70PDGFRBPDGFRA | |
| SCHEMBL13753067 | 0.87 | ZAP70 (0.44) | ZAP70PDGFRBPDGFRA | |
| SCHEMBL13753050 | 0.81 | AURKA (0.40) | ZAP70PDGFRBPDGFRA | |
| SCHEMBL13752991 | 0.81 | ZAP70 (0.48) | ZAP70 | |
| SCHEMBL1050113 | 0.80 | ZAP70 (0.52) | ZAP70CD274PDGFRBPDGFRA | |
| SCHEMBL13753084 | 0.79 | CD274 (0.54) | ZAP70CD274PDGFRBPDGFRA | |
| SCHEMBL13753064 | 0.77 | ZAP70 (0.46) | ZAP70 | |
| SCHEMBL1047731 | 0.77 | ZAP70 (0.67) | ZAP70CD274MEN1KMT2A | |
| SCHEMBL1047007 | 0.77 | ZAP70 (0.62) | ZAP70CD274PDGFRBPDGFRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | disclosed |