SCHEMBL13755128

SCHEMBL13755128

CN1C[C@@H](NC=O)[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)CC1=O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.55
PYGL P06737 8/20 0.52
PYGM P11217 7/20 0.52
F10 P00742 9/20 0.49
SMYD3 Q9H7B4 1/20 0.49
HRH4 Q9H3N8 1/20 0.49
F2 P00734 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13755129 1.00 EHMT2 (0.55) EHMT2PYGLPYGMF10SMYD3
SCHEMBL1503776 0.90 EHMT2 (0.57) EHMT2PYGLPYGMF10SMYD3
SCHEMBL1503775 0.90 EHMT2 (0.57) EHMT2PYGLPYGMF10SMYD3
SCHEMBL3312847 0.86 EHMT2 (0.55) EHMT2PYGLPYGMF10SMYD3
SCHEMBL3312851 0.86 EHMT2 (0.55) EHMT2PYGLPYGMF10SMYD3
SCHEMBL2938178 0.82 EHMT2 (0.51) EHMT2PYGLPYGMF10SMYD3
SCHEMBL2938180 0.82 EHMT2 (0.51) EHMT2PYGLPYGMF10SMYD3
SCHEMBL1253558 0.78 F10 (0.81) F10F2
SCHEMBL1504158 0.78 F10 (0.81) F10F2
SCHEMBL1253560 0.78 F10 (0.81) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576135-B2 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-08-18 US disclosed