Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335590 | 0.93 | GSK3B (0.58) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL2336401 | 0.92 | GSK3B (0.58) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL6530031 | 0.84 | GSK3B (0.50) | GSK3BCDK1CDK2MAPK8MAPK10 | |
| SCHEMBL2338045 | 0.83 | GSK3B (0.62) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL1375621 | 0.83 | GSK3B (0.64) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL2360847 | 0.82 | GSK3B (0.61) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL1378926 | 0.82 | GSK3B (0.61) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL2335712 | 0.80 | GSK3B (0.58) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL2336207 | 0.80 | GSK3B (0.58) | GSK3BCDK1CDK2MAPK8MAPK10 | |
| SCHEMBL6528915 | 0.79 | GSK3B (0.57) | GSK3BCDK1CDK2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764168-B2 | — | — | 2011-08-31 | — | — | JP | claimed |