⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450732 | 0.75 | — | — | |
| SCHEMBL15396104 | 0.74 | — | — | |
| SCHEMBL5061919 | 0.72 | — | — | |
| SCHEMBL8566412 | 0.72 | — | — | |
| SCHEMBL4523034 | 0.72 | — | — | |
| SCHEMBL4400430 | 0.72 | — | — | |
| SCHEMBL23128417 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28419740 | 0.70 | — | — | |
| SCHEMBL5591518 | 0.69 | — | — | |
| SCHEMBL11456170 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579481-B2 | Method of making imidazole-2-ones and 2-thiones | ALLERGAN, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070197795-A1 | METHOD OF MAKING IMIDAZOLE-2-ONES AND 2-THIONES | ALLERGAN, INC. | 2007-08-23 | — | — | US | disclosed |