SCHEMBL13759108

SCHEMBL13759108

CCn1c(O)c(N=Nc2ccc(-c3ccc(N=Nc4c(C)c(C(=O)NC(=O)c5ccc(OC)cc5)c(=O)n(CC)c4O)cc3S(=O)(=O)O)c(S(=O)(=O)O)c2)c(C)c(C(=O)NC(=O)c2ccc(OC)cc2)c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.37
▸ HTT P42858 4/20 0.37
▸ SMN1; SMN2 Q16637 4/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ MAPT P10636 7/20 0.35
▸ POLB P06746 2/20 0.33
▸ TP53 P04637 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ KMT2A Q03164 5/20 0.32
▸ MEN1 O00255 4/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA1 P00915 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ CA9 Q16790 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ HDAC1 Q13547 1/20 0.32
▸ PTPN1 P18031 1/20 0.32
▸ PTPN6 P29350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13751897 0.91 KDM4E (0.32) KDM4EHTTSMN1; SMN2MAPK1MAPT
SCHEMBL13759104 0.90 CA12 (0.40) KDM4EHTTSMN1; SMN2MAPK1MAPT
SCHEMBL13759098 0.87 MAPT (0.35) KDM4EHTTSMN1; SMN2MAPK1MAPT
SCHEMBL13751891 0.83 CA12 (0.34) KDM4EKMT2AMEN1CA12CA1
SCHEMBL13759099 0.81 MAPT (0.38) KDM4ESMN1; SMN2MAPK1MAPTPOLB
SCHEMBL13759107 0.80 MAPT (0.38) KDM4EHTTSMN1; SMN2MAPK1MAPT
SCHEMBL13751886 0.80 POLB (0.30) MAPK1MAPTPOLBATM
SCHEMBL13759106 0.78 KDM4E (0.35) KDM4EHTTMAPK1MAPTPOLB
SCHEMBL13759100 0.76 MAPT (0.47) KDM4ESMN1; SMN2MAPK1MAPTPOLB
SCHEMBL13751885 0.75 MAPT (0.32) MAPK1MAPTPOLBATMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090207287-A1 Colored photosensitive composition, and color filter array and solid image pickup device using the same SONY CORPORATION (JP) 2009-08-20 — — US disclosed
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