⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115431 | 1.00 | — | — | |
| SCHEMBL13494457 | 1.00 | — | — | |
| SCHEMBL2345640 | 0.93 | — | — | |
| SCHEMBL10382344 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL13184894 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL28684669 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL10896704 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL29828938 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL21633008 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL19303361 | 0.91 | KMT2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557211-B2 | 8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-07-07 | — | — | US | disclosed |
| US-7557211-B2 | 8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-07-07 | — | — | US | disclosed |