Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362617 | 1.00 | CHRM3 (0.49) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1364114 | 0.94 | CHRM3 (0.47) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1364195 | 0.92 | CHRM3 (0.51) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1363385 | 0.91 | CHRM3 (0.62) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1362614 | 0.91 | CHRM3 (0.62) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4200694 | 0.91 | PDE4B (0.43) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1362789 | 0.91 | PDE4B (0.44) | CHRM3 | |
| SCHEMBL1362829 | 0.90 | CHRM3 (0.45) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1363313 | 0.90 | CHRM3 (0.49) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1364449 | 0.90 | CHRM3 (0.53) | CHRM3CHRM2CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100168-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |