Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.55 |
| ▸ | HTR2C | P28335 | 10/20 | 0.55 |
| ▸ | HTR2B | P41595 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763030 | 1.00 | HTR2A (0.55) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763057 | 0.90 | HTR2A (0.67) | HTR2AHTR2CHTR2B | |
| SCHEMBL4483372 | 0.84 | HTR2A (0.51) | HTR2AHTR2CHTR2B | |
| SCHEMBL13756865 | 0.81 | HTR2C (0.82) | HTR2AHTR2CHTR2B | |
| SCHEMBL13756868 | 0.81 | HTR2C (0.82) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763139 | 0.80 | HTR2A (0.54) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4467012 | 0.80 | HTR2A (0.83) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4472459 | 0.80 | HTR2A (0.83) | HTR2AHTR2CHTR2B | |
| SCHEMBL4473909 | 0.79 | HTR2A (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL4473912 | 0.79 | HTR2A (0.46) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572805-B2 | Pyrrolo(oxo)isoquinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-11 | — | — | US | disclosed |