Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.60 |
| ▸ | HTR2C | P28335 | 18/20 | 0.60 |
| ▸ | HTR2B | P41595 | 18/20 | 0.60 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763172 | 1.00 | HTR2A (0.60) | HTR2AHTR2CHTR2BPBRM1 | |
| SCHEMBL13763053 | 0.88 | HTR2A (0.64) | HTR2AHTR2CHTR2BPBRM1 | |
| SCHEMBL13763036 | 0.88 | HTR2A (0.64) | HTR2AHTR2CHTR2BPBRM1 | |
| SCHEMBL13763065 | 0.86 | HTR2A (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763176 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763066 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763116 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763014 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763140 | 0.84 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL13763033 | 0.84 | HTR2A (0.64) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572805-B2 | Pyrrolo(oxo)isoquinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-11 | — | — | US | disclosed |