Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136008 | 0.89 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL27469120 | 0.87 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL14797576 | 0.87 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL19112427 | 0.87 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL6128216 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL4085100 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL18211770 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL4085102 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL6128215 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL5442488 | 0.82 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563741-B2 | Silicone composition which can be crosslinked into an elastomer by hydrosilylation in the presence of carbene-based metal catalysts, and catalysts of this type | RHODIA CHIMIE (FR) | 2009-07-21 | — | — | US | disclosed |
| EP-1506251-B1 | SILICONE COMPOSITION WHICH CAN BE CROSSLINKED INTO AN ELASTOMER BY HYDROSILYLATION IN THE PRESENCE OF CARBENE-BASED METAL CATALYSTS, AND CATALYSTS OF THIS TYPE | RHODIA CHIMIE SA (FR) | 2008-10-15 | — | — | EP | disclosed |