Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378962 | 0.95 | HRH3 (1.00) | HRH3 | |
| SCHEMBL1377995 | 0.94 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5025830 | 0.90 | HRH3 (0.89) | HRH3 | |
| SCHEMBL1375917 | 0.90 | HRH3 (0.89) | HRH3 | |
| SCHEMBL1375921 | 0.90 | HRH3 (0.89) | HRH3 | |
| SCHEMBL5022306 | 0.89 | HRH3 (0.89) | HRH3 | |
| SCHEMBL1377980 | 0.88 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5027425 | 0.88 | HRH3 (0.88) | HRH3 | |
| SCHEMBL5023556 | 0.87 | HRH3 (0.85) | HRH3 | |
| SCHEMBL5017110 | 0.87 | HRH3 (0.85) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4652404-B2 | — | — | 2011-03-16 | — | — | JP | claimed |
| EP-1761519-A1 | INDOLE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005123716-A1 | INDOLE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-29 | — | — | WO | claimed |