Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 14/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764496 | 0.92 | SLC5A2 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL1727413 | 0.87 | SLC5A2 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL13764497 | 0.85 | SLC5A2 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL13764480 | 0.82 | SLC5A2 (0.57) | SLC5A2SLC5A1 | |
| SCHEMBL1728449 | 0.81 | SLC5A2 (0.46) | SLC5A2SLC5A1 | |
| SCHEMBL1728486 | 0.81 | SLC5A2 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL1726883 | 0.80 | SLC5A2 (0.45) | SLC5A2SLC5A1 | |
| SCHEMBL1726892 | 0.80 | SLC5A2 (0.45) | SLC5A2SLC5A1 | |
| SCHEMBL1728600 | 0.79 | SLC5A2 (0.52) | SLC5A2SLC5A1 | |
| SCHEMBL1726978 | 0.79 | SLC5A1 (0.52) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |