Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 14/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 14/20 | 0.47 |
| ▸ | CD22 | P20273 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764506 | 0.95 | SLC5A2 (0.46) | SLC5A1SLC5A2 | |
| SCHEMBL13764504 | 0.91 | SLC5A1 (0.45) | SLC5A1SLC5A2 | |
| SCHEMBL13764505 | 0.85 | SLC5A1 (0.48) | SLC5A1SLC5A2 | |
| SCHEMBL1726679 | 0.80 | SLC5A2 (0.54) | SLC5A1SLC5A2 | |
| SCHEMBL1728349 | 0.80 | SLC5A2 (0.50) | SLC5A1SLC5A2 | |
| SCHEMBL1728750 | 0.80 | SLC5A1 (0.51) | SLC5A1SLC5A2 | |
| SCHEMBL1728624 | 0.80 | SLC5A2 (0.51) | SLC5A1SLC5A2HSD17B10KDM4ECYP3A4 | |
| SCHEMBL1728251 | 0.79 | SLC5A2 (0.55) | SLC5A1SLC5A2 | |
| SCHEMBL1726677 | 0.79 | SLC5A1 (0.56) | SLC5A1SLC5A2HSD17B10KDM4ECYP3A4 | |
| SCHEMBL1726690 | 0.79 | SLC5A2 (0.56) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |