Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 20/20 | 0.78 |
| ▸ | NR1H2 | P55055 | 18/20 | 0.78 |
| ▸ | RXRA | P19793 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | VHL | P40337 | 1/20 | 0.78 |
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383609 | 0.88 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL2110041 | 0.88 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL29359875 | 0.88 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL29378086 | 0.87 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL320637 | 0.87 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL29802701 | 0.87 | NR1H3 (1.00) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL14199114 | 0.86 | NR1H3 (0.87) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL4945824 | 0.86 | NR1H3 (0.87) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL3857872 | 0.86 | NR1H3 (0.86) | NR1H3NR1H2RXRAMEN1NR1I2 | |
| SCHEMBL14199136 | 0.86 | NR1H3 (0.86) | NR1H3NR1H2RXRAMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560586-B2 | Acid and ester compounds and methods of using the same | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |