Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883379 | 0.92 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL805698 | 0.92 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL805700 | 0.91 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL290578 | 0.91 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL805630 | 0.90 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL14110580 | 0.90 | S1PR3 (0.84) | S1PR3 | |
| SCHEMBL805671 | 0.90 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL805659 | 0.89 | S1PR3 (1.00) | S1PR3 | |
| SCHEMBL4883950 | 0.89 | S1PR3 (0.85) | S1PR3 | |
| SCHEMBL805697 | 0.89 | S1PR3 (0.85) | S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088531-A1 | 6-SUBSTITUTED INDOLE-3-CARBOXYLIC ACID AMIDE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 2009-07-16 | — | — | WO | disclosed |