SCHEMBL13765331

SCHEMBL13765331

CN(N)c1ncnc2c([C@H]3CC[C@@H](CO)N3)c[nH]c12

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 7/20 0.38
MTAP Q13126 11/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13765269 0.91 PNP (0.37) PNPMTAP
SCHEMBL13765271 0.82 PNP (0.56) PNPMTAP
SCHEMBL30292311 0.82 PNP (0.56) PNPMTAP
SCHEMBL19671141 0.82 PNP (0.56) PNPMTAP
SCHEMBL19671054 0.82 PNP (0.56) PNPMTAP
SCHEMBL3888727 0.82 PNP (0.56) PNPMTAP
SCHEMBL15740272 0.81 PNP (0.40) PNPMTAP
SCHEMBL13765266 0.76 PNP (0.40) PNPMTAP
SCHEMBL3897747 0.75 PNP (0.69) PNPMTAP
SCHEMBL26348070 0.74 PNP (0.40) PNPMTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560434-B2 AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases BIOCRYST PHARMACEUTICALS, INC. (US) 2009-07-14 US disclosed