Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 14/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455166 | 0.93 | S1PR1 (0.57) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3762551 | 0.91 | S1PR1 (0.43) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL10181621 | 0.91 | S1PR1 (0.49) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL10181648 | 0.90 | S1PR1 (0.43) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3758974 | 0.87 | S1PR1 (0.50) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3751169 | 0.87 | S1PR1 (0.49) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3756948 | 0.87 | S1PR1 (0.45) | S1PR1KCNH2 | |
| SCHEMBL3761101 | 0.87 | S1PR1 (0.41) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3755464 | 0.86 | S1PR1 (0.41) | S1PR1S1PR4S1PR5S1PR3KCNH2 | |
| SCHEMBL3748523 | 0.86 | S1PR1 (0.41) | S1PR1S1PR4S1PR5S1PR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080663-A1 | TRIAZOLE OXADIAZOLES DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-07-02 | — | — | WO | disclosed |