Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989163 | 0.91 | S1PR1 (0.60) | S1PR1S1PR3KCNH2 | |
| SCHEMBL2993433 | 0.88 | S1PR1 (0.65) | S1PR1S1PR3KCNH2 | |
| SCHEMBL2605769 | 0.84 | S1PR1 (0.56) | S1PR1S1PR3KCNH2NR1H2 | |
| SCHEMBL13323054 | 0.83 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL1966833 | 0.82 | S1PR1 (0.59) | S1PR1S1PR3 | |
| SCHEMBL2605716 | 0.82 | S1PR1 (0.63) | S1PR1S1PR3KCNH2 | |
| SCHEMBL2605648 | 0.81 | S1PR1 (0.47) | S1PR1S1PR3KCNH2NR1H2 | |
| SCHEMBL2997333 | 0.80 | S1PR1 (0.69) | S1PR1S1PR3KCNH2 | |
| SCHEMBL13012428 | 0.80 | S1PR1 (0.54) | S1PR1S1PR3KCNH2 | |
| SCHEMBL2985518 | 0.79 | S1PR1 (0.54) | S1PR1S1PR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080725-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |