Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.84 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985918 | 0.92 | S1PR1 (0.83) | S1PR1S1PR3CYP2C9S1PR5 | |
| Hydrochloric Acid SCHEMBL2989337 | 0.92 | S1PR1 (0.81) | S1PR1S1PR3CYP2C9S1PR5 | |
| SCHEMBL3053576 | 0.92 | S1PR1 (1.00) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL2986633 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3CYP2C9S1PR5 | |
| Hydrochloric Acid SCHEMBL2981807 | 0.90 | S1PR1 (0.98) | S1PR1S1PR3CYP2C9S1PR5 | |
| SCHEMBL1964979 | 0.89 | S1PR1 (0.80) | S1PR1S1PR3CYP2C9S1PR5 | |
| SCHEMBL3055060 | 0.88 | S1PR1 (1.00) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL2990910 | 0.87 | S1PR1 (0.93) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL12855196 | 0.86 | S1PR1 (0.75) | S1PR1S1PR3CYP2C9S1PR5 | |
| SCHEMBL3662269 | 0.86 | S1PR1 (0.68) | S1PR1S1PR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080725-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |