Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458912 | 0.90 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL2983038 | 0.88 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL2983598 | 0.84 | S1PR1 (0.69) | S1PR1S1PR3S1PR4CYP2C9S1PR5 | |
| Hydrochloric Acid SCHEMBL2986372 | 0.84 | S1PR1 (0.68) | S1PR1S1PR3S1PR4CYP2C9S1PR5 | |
| SCHEMBL2168613 | 0.83 | S1PR1 (0.84) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2179933 | 0.83 | S1PR1 (0.79) | S1PR1S1PR3S1PR4CYP2C9S1PR5 | |
| SCHEMBL2181741 | 0.83 | S1PR1 (0.79) | S1PR1S1PR3S1PR4CYP2C9S1PR5 | |
| SCHEMBL10455382 | 0.82 | S1PR1 (0.66) | S1PR1S1PR3 | |
| SCHEMBL13765561 | 0.82 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3068298 | 0.81 | S1PR1 (0.63) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080725-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |