Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 2/20 | 0.39 |
| ▸ | GALR1 | P47211 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766119 | 0.92 | TRPV1 (0.43) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL3880752 | 0.90 | TRPV1 (0.47) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL3879871 | 0.89 | TRPV1 (0.48) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL13761516 | 0.89 | TRPV1 (0.48) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL3877829 | 0.89 | GALR2 (0.49) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL13761487 | 0.88 | TRPV1 (0.48) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL3991603 | 0.85 | HSD17B10 (0.43) | HSD17B10MAPK1KDM4ETP53ALDH1A1 | |
| SCHEMBL3885588 | 0.84 | TRPV1 (0.49) | TRPV1GALR2GALR1 | |
| SCHEMBL3879767 | 0.84 | TRPV1 (0.49) | TRPV1GALR2GALR1 | |
| SCHEMBL3881431 | 0.84 | TRPV1 (0.42) | HSD17B10KDM4ETRPV1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |