Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958820 | 0.91 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL3966455 | 0.88 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL3963939 | 0.87 | KCNH2 (0.63) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3967248 | 0.87 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL3960494 | 0.86 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL3964812 | 0.80 | KCNH2 (0.66) | KCNH2 | |
| SCHEMBL3955966 | 0.80 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL3958798 | 0.78 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL3963991 | 0.78 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL3963885 | 0.77 | KCNH2 (0.60) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080761-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2009-07-22 | — | — | EP | disclosed |