Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 17/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963244 | 0.90 | KCNH2 (0.46) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3963252 | 0.83 | KCNH2 (0.46) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3964408 | 0.83 | KCNH2 (0.47) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3962526 | 0.82 | KCNH2 (0.45) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3959368 | 0.81 | KCNH2 (0.46) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3962074 | 0.80 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL10313923 | 0.79 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL12047114 | 0.79 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL3961591 | 0.79 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL12047121 | 0.79 | KCNH2 (0.46) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080761-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2009-07-22 | — | — | EP | disclosed |