Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018405 | 0.89 | PPARD (0.57) | PPARDPPARA | |
| SCHEMBL10224791 | 0.87 | PPARD (0.52) | PPARDPPARA | |
| SCHEMBL13680155 | 0.86 | PPARD (0.54) | PPARDPPARA | |
| SCHEMBL13767993 | 0.84 | PPARD (0.45) | PPARDPPARA | |
| SCHEMBL10226001 | 0.84 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL13767911 | 0.84 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL13680148 | 0.84 | PPARD (0.47) | PPARDPPARA | |
| SCHEMBL13680159 | 0.84 | PPARD (0.64) | PPARDPPARA | |
| SCHEMBL13768084 | 0.80 | PPARD (0.44) | PPARDPPARA | |
| SCHEMBL13680157 | 0.79 | PPARD (0.66) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667964-B1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | EP | disclosed |