Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691931 | 0.81 | PDPK1 (0.44) | KDM4EALDH1A1TSHRCYP1A2CYP2C19 | |
| SCHEMBL13824699 | 0.77 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13767966 | 0.76 | KDM4E (0.51) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL4007677 | 0.76 | CDC7 (0.52) | SMN1; SMN2ALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL13824780 | 0.74 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13824795 | 0.74 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13824797 | 0.74 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13824639 | 0.72 | PNP (0.51) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13824776 | 0.72 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL13824640 | 0.71 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |
| WO-2009082247-A1 | PROCESS FOR PREPARING IMMUCILLINS HAVING A METHYLENE LINK | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-07-02 | — | — | WO | disclosed |