Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768663 | 0.95 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL13772390 | 0.85 | EPHX2 (0.42) | EPHX2 | |
| SCHEMBL13768502 | 0.84 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL13768661 | 0.83 | EPHX2 (0.37) | EPHX2 | |
| SCHEMBL13768667 | 0.83 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL13768665 | 0.82 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL13768662 | 0.81 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL4010714 | 0.78 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL3226878 | 0.78 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL4010983 | 0.78 | EPHX2 (0.69) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086429-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |