Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.32 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12558152 | 0.63 | LATS1 (0.59) | LATS1LATS2NUDT1 | |
| SCHEMBL23262169 | 0.58 | MAPK8 (0.75) | — | |
| SCHEMBL14657504 | 0.58 | MAPK8 (0.75) | — | |
| SCHEMBL14657505 | 0.58 | MAPK8 (0.75) | — | |
| SCHEMBL14671110 | 0.57 | MAPK8 (0.55) | NUDT1 | |
| SCHEMBL17103716 | 0.57 | LATS1 (0.38) | LATS1LATS2NUDT1 | |
| SCHEMBL22490032 | 0.57 | LATS1 (0.36) | LATS1LATS2NUDT1BCDIN3D | |
| SCHEMBL12984990 | 0.57 | MEN1 (0.42) | LATS1LATS2NUDT1BCDIN3D | |
| SCHEMBL12985215 | 0.56 | LATS1 (0.36) | LATS1LATS2 | |
| SCHEMBL12985211 | 0.56 | LATS1 (0.36) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085185-A1 | FUSED PYRIDINE, PYRIMIDINE AND TRIAZINE COMPOUNDS AS CELL CYCLE INHIBITORS | AMGEN INC. (US) | 2009-07-09 | — | — | WO | disclosed |