Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255044 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL5237763 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL16673562 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL23377075 | 0.78 | SLC6A4 (0.49) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL12339309 | 0.75 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8851916 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL29957653 | 0.75 | SLC6A2 (0.42) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL13885993 | 0.75 | SLC6A2 (0.51) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL8851640 | 0.75 | SLC6A2 (0.42) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL8851385 | 0.75 | SLC6A2 (0.42) | SLC6A2SLC6A4NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701944-B1 | 2-(AMINO-SUBSTITUTED)-4-ARYL PYRAMIDINES AND RELATED COMPOUNDS USEFUL FOR TREATING INFLAMMATORY DISEASES | MILLENNIUM PHARM INC (US) | 2009-07-29 | — | — | EP | disclosed |