Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377313 | 0.97 | SCD (0.66) | SCD | |
| SCHEMBL1380775 | 0.91 | SCD (0.62) | SCD | |
| SCHEMBL1377535 | 0.91 | SCD (0.67) | SCD | |
| SCHEMBL1380904 | 0.87 | SCD (0.70) | SCD | |
| SCHEMBL5596966 | 0.87 | SCD (0.72) | SCD | |
| SCHEMBL1380085 | 0.86 | SCD (0.69) | SCD | |
| SCHEMBL1601232 | 0.85 | SCD (0.68) | SCD | |
| SCHEMBL1377918 | 0.85 | SCD (0.62) | SCD | |
| SCHEMBL1377776 | 0.85 | SCD (0.65) | SCD | |
| SCHEMBL1378549 | 0.84 | SCD (0.81) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4808616-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | disclosed |
| US-7964591-B2 | Pyridazine derivatives and their use as therapeutic agents | NOVARTIS PHARMA AG (CH) | 2011-06-21 | — | — | US | disclosed |
| US-7919484-B2 | Combination therapy | XENON PHARMACEUTICALS INC. (CA) | 2011-04-05 | — | — | US | disclosed |