Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737684 | 1.00 | HRH3 (0.46) | HRH3CXCR4KCNH2 | |
| SCHEMBL737100 | 1.00 | HRH3 (0.46) | HRH3CXCR4KCNH2 | |
| Hydrochloric Acid SCHEMBL30356123 | 0.98 | CXCR4 (0.46) | HRH3CXCR4KCNH2 | |
| SCHEMBL2115516 | 0.94 | CXCR4 (0.51) | HRH3CXCR4 | |
| SCHEMBL25021648 | 0.88 | CXCR4 (0.50) | HRH3CXCR4 | |
| SCHEMBL5500569 | 0.88 | HRH3 (0.39) | HRH3CXCR4 | |
| SCHEMBL2882268 | 0.87 | — | — | |
| SCHEMBL2876828 | 0.87 | — | — | |
| SCHEMBL13144667 | 0.87 | — | — | |
| SCHEMBL23828676 | 0.87 | HRH3 (0.52) | HRH3CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391692-B1 | Process for producing high trans low vinyl conjugated diene (co) polymer | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1994-01-05 | — | — | EP | claimed |
| US-5086136-A | Using coordination catalyst containing organoaluminum compound, barium compound and alcohol | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-02-04 | — | — | US | claimed |
| EP-0391692-A1 | Process for producing high trans low vinyl conjugated diene (co) polymer | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-10-10 | — | — | EP | claimed |
| US-12172980-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | XWPharma Ltd. (KY) | 2024-12-24 | — | — | US | disclosed |
| EP-3856719-B1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPHARMA LTD (KY) | 2023-06-07 | — | — | EP | disclosed |
| US-20220380339-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2022-12-01 | — | — | US | disclosed |
| US-11420955-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | XWPharma Ltd. (KY) | 2022-08-23 | — | — | US | disclosed |
| CN-114042070-A | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-112004802-B | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2021-12-28 | — | — | CN | disclosed |
| EP-3856719-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2021-08-04 | — | — | EP | disclosed |
| US-20210188808-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2021-06-24 | — | — | US | disclosed |
| WO-2007048595-A1 | COMPOUNDS COMPRISING A LACTAM OR A LACTAM DERIVATIVE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-05-03 | — | — | WO | disclosed |
| WO-2006103045-A1 | COMPOUNDS COMPRISING AN OXAZOLE OR THIAZOLE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA S.A. (BE) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006103057-A1 | COMPOUNDS COMPRISING AN OXAZOLINE OR THIAZOLINE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA, S.A. (BE) | 2006-10-05 | — | — | WO | disclosed |
| EP-0609010-B1 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORP (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5527860-A | PROMOTER IS REACTION PRODUCT OF A SECONDARY AMINE AND ORGANOLITHIUM COMPOUND OR ALCOHOL AND A LITHIUM ALKOXIDE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0609010-A2 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORPORATION (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0391692-B1 | Process for producing high trans low vinyl conjugated diene (co) polymer | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5086136-A | Using coordination catalyst containing organoaluminum compound, barium compound and alcohol | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0391692-A1 | Process for producing high trans low vinyl conjugated diene (co) polymer | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380339-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | HRH3 1/4885CXCR4 461/4885KCNH2 763/4885 |
| US-12172980-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | HRH3, HRH4, HRH2 | HRH3 1/4885CXCR4 481/4885KCNH2 499/4885 |
| US-20210188808-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | HRH3 1/4885CXCR4 481/4885KCNH2 499/4885 |
| US-11420955-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | HRH3, HRH4, HRH2 | HRH3 1/4885CXCR4 481/4885KCNH2 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.