Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648103 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL648375 | 0.97 | DPP4 (0.95) | DPP4DPP8DPP9 | |
| SCHEMBL1380368 | 0.97 | DPP4 (0.95) | DPP4DPP8DPP9 | |
| SCHEMBL646491 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL646165 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1379597 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1377505 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL646199 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1380419 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1381970 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4712387-B2 | — | — | 2011-06-29 | — | — | JP | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |