Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12226879 | 0.88 | PDE2A (0.41) | CDK1CDK4CDK2MEN1GAA | |
| SCHEMBL8283870 | 0.83 | TNF (0.41) | HTTKMT2ANOD1TNFNOD2 | |
| SCHEMBL8283878 | 0.82 | TNF (0.40) | CDK1CDK4CDK2HTTKMT2A | |
| SCHEMBL13773411 | 0.82 | CDK1 (0.45) | CDK1CDK4CDK2ACSS2GAA | |
| SCHEMBL8283871 | 0.80 | NPC1 (0.48) | MEN1MAPTHTTKMT2AALDH1A1 | |
| SCHEMBL8283872 | 0.77 | TNF (0.41) | HTTKMT2ANOD1TNFNOD2 | |
| SCHEMBL8285693 | 0.76 | TNF (0.40) | HTTKMT2ANOD1TNFNOD2 | |
| SCHEMBL8285557 | 0.74 | ADORA2A (0.44) | KMT2ANOD1TNFNOD2ALDH1A1 | |
| SCHEMBL13773410 | 0.72 | CDK1 (0.42) | CDK1CDK4CDK2KMT2ANOD1 | |
| SCHEMBL8284609 | 0.71 | NPC1 (0.45) | CDK1CDK4CDK2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697343-B1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2009-07-01 | — | — | EP | disclosed |