SCHEMBL137750

SCHEMBL137750

CCCC1([Zr](Cl)(Cl)C2(CCC)C=Cc3ccccc32)C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
OXTR P30559 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196700 0.90 KDM4E (0.35) KDM4EPKM
SCHEMBL7196710 0.86 KDM4E (0.32) KDM4EPKM
SCHEMBL1130904 0.83 KDM4E (0.33) KDM4EPKMOXTR
SCHEMBL6558663 0.80
SCHEMBL6295904 0.75
SCHEMBL1130446 0.74 KDM4E (0.35) KDM4EPKM
SCHEMBL20563812 0.74 KDM4E (0.33) KDM4EPKMOXTR
SCHEMBL23924806 0.73 KDM4E (0.38) KDM4EPKMOXTR
SCHEMBL813298 0.70 KDM4E (0.36) KDM4EPKMOXTR
SCHEMBL18378582 0.70 KDM4E (0.36) KDM4EPKMOXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614095-B1 NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2015-08-26 EP claimed
US-8932975-B2 Catalyst systems and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-01-13 US claimed
US-20120059134-A1 Novel Catalyst Systems and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-08 US claimed
EP-3209723-B1 POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2020-05-13 EP disclosed
US-9994659-B2 Polymers with improved processability for pipe applications CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-06-12 US disclosed
US-20180044454-A1 Polymers with Improved Processability for Pipe Applications CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-02-15 US disclosed
US-9828451-B2 Polymers with improved processability for pipe applications CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-11-28 US disclosed
EP-3209723-A1 POLYMERS WITH IMPROVED PROCESSABILITY FOR PIPE APPLICATIONS Chevron Phillips Chemical Company LP (US) 2017-08-30 EP disclosed
EP-2751145-B1 POLYMER COMPOSITIONS HAVING IMPROVED BARRIER PROPERTIES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-07-19 EP disclosed
US-9637573-B2 Polymer compositions and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-05-02 US disclosed
EP-2951213-B1 CATALYST COMPOSITIONS, METHODS OF MAKING THEM AND THEIR USE CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-03-29 EP disclosed
US-20130059100-A1 Polymer Compositions Having Improved Barrier Properties CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-07 US disclosed
WO-2012033670-A1 NOVEL CATALYST SYSTEMS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-15 WO disclosed
US-20120059134-A1 Novel Catalyst Systems and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-08 US disclosed
US-7141632-B2 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator UNIVATION TECHNOLOGIES, LLC (US) 2006-11-28 US disclosed
US-7060765-B2 Low comonomer incorporating metallocene catalyst compounds UNIVATION TECHNOLOGIES, LLC (US) 2006-06-13 US disclosed
US-6828394-B2 Used for copolymerizing ethylene to form a copolymer having a bimodal molecular weight distribution UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-20040225088-A1 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator VAUGHAN GEORGE ALAN (US) 2004-11-11 US disclosed
US-20040077785-A1 Low comonomer incorporating metallocene catalyst compounds UNIVATION TECHNOLOGIES, LLC 2004-04-22 US disclosed
US-20030088038-A1 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator UNIVATION TECHNOLOGIES, LLC 2003-05-08 US disclosed