⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965147 | 0.73 | — | — | |
| SCHEMBL11582002 | 0.73 | — | — | |
| SCHEMBL11585439 | 0.73 | — | — | |
| SCHEMBL762744 | 0.73 | — | — | |
| SCHEMBL3408372 | 0.73 | — | — | |
| SCHEMBL7612224 | 0.71 | — | — | |
| SCHEMBL21567763 | 0.71 | — | — | |
| SCHEMBL1164270 | 0.71 | — | — | |
| SCHEMBL18964394 | 0.71 | — | — | |
| SCHEMBL14240875 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850234-B2 | Pyridine derivatives as soft rock inhibitors | REDX PHARMA PLC (GB) | 2017-12-26 | — | — | US | disclosed |
| US-20170247357-A1 | PYRIDINE DERIVATIVES AS SOFT ROCK INHIBITORS | REDX PHARMA PLC (GB) | 2017-08-31 | — | — | US | disclosed |
| US-9682963-B2 | Pyridine derivatives as soft rock inhibitors | REDX PHARMA PLC (GB) | 2017-06-20 | — | — | US | disclosed |
| EP-2951172-B1 | PYRIDINE DERIVATIVES AS SOFT ROCK INHIBITORS | AMAKEM NV (BE) | 2017-03-29 | — | — | EP | disclosed |
| US-20150361072-A1 | PYRIDINE DERIVATIVES AS SOFT ROCK INHIBITORS | AMAKEM NV (BE) | 2015-12-17 | — | — | US | disclosed |
| EP-2951172-A1 | PYRIDINE DERIVATIVES AS SOFT ROCK INHIBITORS | Amakem NV (BE) | 2015-12-09 | — | — | EP | disclosed |
| CN-105026387-A | Pyridine derivatives as soft rock inhibitors | AMAKEM NV | 2015-11-04 | — | — | CN | disclosed |
| WO-2014118133-A1 | PYRIDINE DERIVATIVES AS SOFT ROCK INHIBITORS | AMAKEM NV (BE) | 2014-08-07 | — | — | WO | disclosed |
| US-7556908-B2 | Chemically amplified positive resist composition, (meth)acrylate derivative and a process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7556908-B2 | Chemically amplified positive resist composition, (meth)acrylate derivative and a process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7232642-B2 | Chemically amplified positive resist composition, a haloester derivative and a process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-19 | — | — | US | disclosed |
| US-7232642-B2 | Chemically amplified positive resist composition, a haloester derivative and a process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-19 | — | — | US | disclosed |