Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.46 |
| ▸ | PPARG | P37231 | 14/20 | 0.46 |
| ▸ | PPARD | Q03181 | 9/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952370 | 1.00 | PPARA (0.46) | PPARAPPARGPPARDPTPN1ADAMTS4 | |
| SCHEMBL5850587 | 0.81 | PPARA (0.49) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL3959780 | 0.79 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL13780393 | 0.79 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3956363 | 0.79 | PPARD (0.58) | PPARAPPARGPPARD | |
| SCHEMBL2067931 | 0.79 | PPARD (0.58) | PPARAPPARGPPARD | |
| SCHEMBL3959758 | 0.79 | PPARD (0.43) | PPARAPPARGPPARD | |
| SCHEMBL5850970 | 0.77 | PTPN1 (0.58) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL3957383 | 0.76 | PPARD (0.48) | PPARAPPARGPPARD | |
| SCHEMBL13780399 | 0.76 | PPARD (0.48) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | disclosed |
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | MANTLO NATHAN BRYAN | 2009-07-09 | — | — | US | disclosed |
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176863-A1 | THIOPHENE DERIVATIVE PPAR MODULATORS | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.