Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13579957 | 1.00 | KMT2A (0.44) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL6647123 | 0.94 | EPHX1 (0.48) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL7817045 | 0.88 | EPHX1 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL14548191 | 0.88 | EPHX1 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL228180 | 0.87 | EPHX1 (0.50) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL6617889 | 0.87 | CYP2D6 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL7162104 | 0.87 | CYP2D6 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL7158318 | 0.87 | CYP2D6 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL7161245 | 0.87 | CYP2D6 (0.43) | KMT2AEPHX1BTKDRD2ACACB | |
| SCHEMBL7162108 | 0.87 | CYP2D6 (0.43) | KMT2AEPHX1BTKDRD2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566734-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-07-28 | — | — | US | disclosed |