Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.76 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | PRKDC | P78527 | 1/20 | 0.64 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924613 | 0.93 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL29903215 | 0.92 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884103 | 0.92 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884101 | 0.92 | PIK3CG (0.90) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL954290 | 0.92 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9883990 | 0.91 | PIK3CG (0.73) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL955596 | 0.90 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL29479406 | 0.90 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884188 | 0.90 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884196 | 0.90 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088990-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |